Simon Oakley

Doctor of Philosophy, (Chemistry)
Study Completed: 2009
College of Sciences

Citation

Thesis Title
Crystallographic Determination of Wild Type, Mutant and Substrate-Analogue Inhibited Structures of Bacterial Members of a Family of Superoxide Dismutases

Read article at Massey Research Online: MRO icon

Mr Oakley investigated bacterial proteins that provide protection from an oxygen-derived free radical.  These enzymes are capable of activity with diverse metal ion cofactors, seemingly defying predictions derived from the Periodic Table of Elements.  Mr Oakley’s studies provide insight into the chemical and electronic processes that occur within the active site of this family of enzymes.

Supervisors
Professor Geoff Jameson
Dr Bryan Anderson
Professor Jw Whittaker

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